Heterogeneous Effects of IL-2 on Collagen-Induced Arthritis

IL-4 Can Inhibit IL-17 Production in Collagen Induced Arthritis

Background: IL-4 is a cytokine that induces differentiation of naive helper T cells into Th2 cells. Once activated by IL-4, Th2 cells subsequently produce additional IL-4. Objective: To examine the effect of IL-4 on IL-17 production and its effect in Collagen- Induced Arthritis (CIA) mice. Method: In this study, a chicken collagen-II-induced experimental arthritis (CIA) model was used in DBA/1 ...

Induction of Collagen-Induced Arthritis Combined Effects of IL-12 and IL-18 on the

IL-1R Type 2 Suppresses Collagen-Induced Arthritis by Inhibiting IL-1 Signal on Macrophages

Effects of cyclosporin on collagen induced arthritis in mice.

We have studied the effect of the immunosuppressive agent cyclosporin on collagen induced arthritis in mice. Cyclosporin, when given prophylactically, was capable of suppressing the development of collagen induced arthritis and the immunological response to native type II collagen in a dose dependent manner. Furthermore, treatment with cyclosporin, started on the same day as the booster injecti...

il-4 can inhibit il-17 production in collagen induced arthritis

background: il-4 is a cytokine that induces differentiation of naive helper t cells into th2 cells. once activated by il-4, th2 cells subsequently produce additional il-4. objective: to examine the effect of il-4 on il-17 production and its effect in collagen- induced arthritis (cia) mice. method: in this study, a chicken collagen-ii-induced experimental arthritis (cia) model was used in dba/1 ...